
Publications
Zhang, X., H. Chen, S. Le, I. Rouzina, P. S. Doyle, and J. Yan. 2013. Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry. Proceedings of the National Academy of Sciences of the United States of America 110:3865-3870.
Le, S., H. Chen, P. Cong, J. Lin, P. Droge, and J. Yan. 2013. Mechanosensing of DNA bending in a single specific protein-DNA complex. Scientific reports 3:3508.
Fu, H., S. Le, H. Chen, K. Muniyappa, and J. Yan. 2013. Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein. Nucleic Acids Res 41:924-932.
Chen, H., S. Chandrasekar, M. P. Sheetz, T. P. Stossel, F. Nakamura, and J. Yan. 2013. Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function. Scientific reports 3:1642.
Zhang, X., H. Chen, H. Fu, P. S. Doyle, and J. Yan. 2012. Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements. Proceedings of the National Academy of Sciences of the United States of America 109:8103-8108.
Lin, J., H. Chen, P. Droge, and J. Yan. 2012. Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF). PloS one 7:e49885.
Fu, H., H. Chen, X. Zhang, Y. Qu, J. F. Marko, and J. Yan. 2011. Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching. Nucleic Acids Res 39:3473-3481 (co-first author).
Chen, H., X. Zhu, P. Cong, M. P. Sheetz, F. Nakamura, and J. Yan. 2011. Differential mechanical stability of filamin A rod segments. Biophys J 101:1231-1237.
Chen, H., H. Fu, X. Zhu, P. Cong, F. Nakamura, and J. Yan. 2011. Improved high-force magnetic tweezers for stretching and refolding of proteins and short DNA. Biophys J 100:517-523.
Liu, Y., J. Wu, H. Chen, C. L. Hew, and J. Yan. 2010. DNA condensates organized by the capsid protein VP15 in White Spot Syndrome Virus. Virology 408:197-203.
Liu, Y., H. Chen, L. J. Kenney, and J. Yan. 2010. A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes. Genes Dev 24:339-344 (co-first author).
Fu, W. B., H. Chen, M. Li, and J. Yan. 2010. Kinetics of Single DNA Compaction by Hexaammine Cobalt Chloride. Journal of Computational and Theoretical Nanoscience 7:213-217.
Fu, H. X., H. Chen, J. Yan, and C. T. Lim. 2010. Salt Solution Effects on Overstretching Transitions of DNA Molecules. Journal of Computational and Theoretical Nanoscience 7:1272-1278.
Fu, H., H. Chen, J. F. Marko, and J. Yan. 2010. Two distinct overstretched DNA states. Nucleic Acids Res 38:5594-5600.
Chen, H., H. X. Fu, Z. Zhou, and J. Yan. 2010. Non-harmonic DNA bending elasticity is revealed by statistics of DNA minicircle shapes. International Journal of Modern Physics B 24:5475-5485.
Fu, H., H. Chen, C. G. Koh, and C. T. Lim. 2009. Effects of magnesium salt concentrations on B-DNA overstretching transition. Eur Phys J E Soft Matter 29:45-49.
Chen, H., Y. Liu, Z. Zhou, L. Hu, Z. C. Ou-Yang, and J. Yan. 2009. Temperature dependence of circular DNA topological states. Phys Rev E Stat Nonlin Soft Matter Phys 79:041926.
Chen, H., and J. Yan. 2008. Effects of kink and flexible hinge defects on mechanical responses of short double-stranded DNA molecules. Phys Rev E Stat Nonlin Soft Matter Phys 77:041907.
Chen, H., H. X. Fu, and C. G. Koh. 2008. Sequence-Dependent Unpeeling Dynamics of Stretched DNA Double Helix. Journal of Computational and Theoretical Nanoscience 5:1381-1386.
Fu, H. X., C. G. Koh, H. Chen, and C. T. Lim. 2007. Experimental and numerical studies on B-DNA overstretching transition in presence of sodium ions at physiological temperature. In Nanoscience and Technology, Pts 1 and 2. C. Bai, S. Xie, and X. Zhu, editors. 1093-1096.
Bao, Q., H. Chen, Y. Liu, J. Yan, P. Droge, and C. A. Davey. 2007. A divalent metal-mediated switch controlling protein-induced DNA bending. J Mol Biol 367:731-740.
Fu, H. X., C. G. Koh, and H. Chen. 2005. Ionic effects on overstretching transition of B-DNA. European Physical Journal E 17:231-235.
Chen, H., C. G. Koh, and C. Y. Liaw. 2005. Accessibility of compact structures and prion-like protein folding property. Modern Physics Letters B 19:1241-1252.
Zhou, X., H. Chen, and M. Iwamoto. 2004. Orientation orders of small anisotropic molecules in confinement. In Slow Dynamics in Complex Systems. M. Tokuyama, and I. Oppenheim, editors. 170-171.
Zhou, X., H. Chen, and M. Iwamoto. 2004. Orientational order in binary mixtures of hard Gaussian overlap molecules. Journal of Chemical Physics 120:1832-1836.
Zhou, X., H. Chen, and M. Iwamoto. 2004. Orientational orders of small anisotropic molecules confined in slit pores. Journal of Chemical Physics 120:5322-5326.
Chen, H., X. Zhou, C. Y. Liaw, and C. G. Koh. 2004. Kinetic analysis of protein folding lattice models. Modern Physics Letters B 18:163-172.
Zhou, X., H. Chen, and M. Iwamoto. 2002. Nonunique steady states in the disordered harmonic chain. Phys Rev E Stat Nonlin Soft Matter Phys 66:061202.
Chen, H., X. Zhou, and Z. C. Ou-Yang. 2002. Classification of amino acids based on statistical results of known structures and cooperativity of protein folding. Phys Rev E Stat Nonlin Soft Matter Phys 65:061907.
Zhou, X., H. Chen, J. J. Zhou, and Z. C. Ou-Yang. 2001. The structure relaxation of carbon nanotube. Physica B 304:86-90.
Zhou, X., H. Chen, and Z. C. Ou-Yang. 2001. Can electric field induced energy gaps in metallic carbon nanotubes? J. Phys.-Condes. Matter 13:L635-L640.
Chen, H., X. Zhou, and Z. C. Ou-Yang. 2001. Difference between "proteinlike" and "nonproteinlike" heteropolymers. Phys Rev E Stat Nonlin Soft Matter Phys 63:031913.
Chen, H., X. Zhou, and Z. C. Ou-Yang. 2001. Secondary-structure-favored hydrophobic-polar lattice model of protein folding. Phys Rev E Stat Nonlin Soft Matter Phys 64:041905.