Lin Youhui-厦大物理科学与技术学院

Research

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Lin Youhui

Associate Professor

linyouhui@xmu.edu.cn

Room 312, Physics Building

website:

Research AreasSynthesis and characterization of functionalized nanomaterials and their applications in artificial enzyme, biosensing, and logic device. Study of molecular recognition, biological functions of disease–related nucleic acids or proteins. Study of the nanomaterials-based biodevice, surface chemistry and nanomedicine.

Publications

1. Lin Youhui; Ren, J.; Qu, X., Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes. Acc Chem Res 2014, 47 (4), 1097-1105.
2. Lin Youhui*; Chen, Z.; Liu, X. Y., Using Inorganic Nanomaterials to Endow Biocatalytic Systems with Unique Features. Trends in Biotechnology 2016.
3. Lin Youhui; Zhao, A.; Tao, Y.; Ren, J.; Qu, X., Ionic Liquid as an Efficient Modulator on Artificial Enzyme System: Toward the Realization of High-Temperature Catalytic Reactions. Journal of the American Chemical Society 2013, 135 (11), 4207-4210.
4. Lin Youhui; Xu, C.; Ren, J.; Qu, X., Using Thermally Regenerable Cerium Oxide Nanoparticles in Biocomputing to Perform Label-free, Resettable, and Colorimetric Logic Operations. Angewandte Chemie-International Edition 2012, 51 (50), 12579-12583.
5. Lin Youhui; Ren, J.; Qu, X., Nano-Gold as Artificial Enzymes: Hidden Talents. Advanced Materials 2014, 26 (25), 4200-4217.
6. Lin Youhui; Wu, L.; Huang, Y.; Ren, J.; Qu, X., Positional assembly of hemin and gold nanoparticles in graphene-mesoporous silica nanohybrids for tandem catalysis. Chemical Science 2015, 6 (2), 1272-1276.
7. Lin Youhui; Tao, Y.; Pu, F.; Ren, J.; Qu, X., Combination of Graphene Oxide and Thiol-Activated DNA Metallization for Sensitive Fluorescence Turn-On Detection of Cysteine and Their Use for Logic Gate Operations. Advanced Functional Materials 2011, 21 (23), 4565-4572.
8. Lin Youhui; Huang, Y.; Ren, J.; Qu, X., Incorporating ATP into biomimetic catalysts for realizing exceptional enzymatic performance over a broad temperature range. Npg Asia Materials 2014, 6.
9. Lin Youhui; Li, Z.; Chen, Z.; Ren, J.; Qu, X., Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis. Biomaterials 2013, 34(11), 2600-2610.
10. Lin Youhui; Yin, M.; Pu, F.; Ren, J.; Qu, X., DNA-Templated Silver Nanoparticles as a Platform for Highly Sensitive and Selective Fluorescence Turn-On Detection of Dopamine. Small 2011, 7 (11), 1557-1561.
11. Lin Youhui; Chen, C.; Wang, C.; Pu, F.; Ren, J.; Qu, X., Silver nanoprobe for sensitive and selective colorimetric detection of dopamine via robust Ag-catechol interaction. Chemical Communications 2011, 47 (4), 1181-1183.
12. Lin Youhui; Tao, Y.; Ren, J.; Pu, F.; Qu, X., Highly sensitive and selective detection of thiol-containing biomolecules using DNA-templated silver deposition. Biosensors & Bioelectronics 2011, 28 (1), 339-343.
13. Yaoping Jiang; Wenhao Luo; Xiaopei Wang; Youhui Lin*; Xiang Yang Liu; Enzymatic Manipulation of DNA-mediated Ensemble for Sensitive Fluorescence Detection of Glucose. RSC Adv., 2016, DOI: 10.1039/c6ra05701b.
14. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Poly(acrylic acid)-templated silver nanoclusters as a platform for dual fluorometric turn-on and colorimetric detection of mercury (II) ions. Talanta 2012, 88, 290-294.
15. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets. Analyst 2012, 137 (11), 2588-2592.
16. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Incorporating Graphene Oxide and Gold Nanoclusters: A Synergistic Catalyst with Surprisingly High Peroxidase-Like Activity Over a Broad pH Range and its Application for Cancer Cell Detection. Advanced Materials 2013, 25 (18), 2594-2599.
17. Tao, Y.; Lin, Y.; Ren, J.; Qu, X., Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays. Biomaterials 2013, 34 (20), 4810-4817.
18. Tao, Y.; Lin, Y.; Ren, J.; Qu, X., A dual fluorometric and colorimetric sensor for dopamine based on BSA-stabilized Au nanoclusters. Biosensors & Bioelectronics 2013, 42, 41-46.
19. Wang, C.; Huang, Z.; Lin, Y.; Ren, J.; Qu, X., Artificial DNA Nano-Spring Powered by Protons. Advanced Materials 2010, 22 (25), 2792-+.
20. Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohn, C.; Nakatani, K.; Qu, X., Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network. Chemistry-a European Journal 2011, 17 (29), 8189-8194.
21. Wang, C.; Tao, Y.; Lin, Y.; Ren, J.; Qu, X., A thermo-driven DNA zipper. Chemical Communications 2013, 49 (96), 11281-11283.
22. Wang, L.; Jiang, Y.; Lin, Y.; Pang, J.; Liu, X. Y., Rheological properties and formation mechanism of DC electric fields induced konjac glucomannan-tungsten gels. Carbohydrate Polymers 2016, 142, 293-299.
23. Xu, C.; Lin, Y.; Wang, J.; Wu, L.; Wei, W.; Ren, J.; Qu, X., Nanoceria-Triggered Synergetic Drug Release Based on CeO2-Capped Mesoporous Silica Host-Guest Interactions and Switchable Enzymatic Activity and Cellular Effects of CeO2. Advanced Healthcare Materials 2013, 2 (12), 1591-1599.
24. Yu, R.; Meng, Z. H.; Ye, M. D.; Lin, Y. H.; Lin, N. B.; Liu, X. Y.; Yu, W. D.; Liu, X. Y., Electrochromic performance of WO3 films: optimization by crystal network topology modification. CrystEngComm 2015, 17 (34), 6583-6590.
25. Zhou, L.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Carbon nanodots as fluorescence probes for rapid, sensitive, and label-free detection of Hg2+ and biothiols in complex matrices. Chemical Communications 2012, 48 (8), 1147-1149.
26. Chen, Z.; Li, Z.; Lin, Y.; Yin, M.; Ren, J.; Qu, X., Bioresponsive Hyaluronic Acid-Capped Mesoporous Silica Nanoparticles for Targeted Drug Delivery. Chemistry-a European Journal 2013, 19 (5), 1778-1783.
27. Chen, Z.; Li, Z.; Lin, Y.; Yin, M.; Ren, J.; Qu, X., Biomineralization inspired surface engineering of nanocarriers for pH-responsive, targeted drug delivery. Biomaterials 2013, 34 (4), 1364-1371.
28. Chen, Z.; Lin, Y.; Zhao, C.; Ren, J.; Qu, X., Silver metallization engineered conformational switch of G-quadruplex for fluorescence turn-on detection of biothiols. Chemical Communications 2012, 48 (93), 11428-11430.
29. Chen, Z.; Zhou, L.; Zhao, A.; Zhang, Z.; Wang, Z.; Lin, Y.; Ren, J.; Qu, X., Coupling exonuclease III with DNA metallization for amplified detection of biothiols at picomolar concentration. Biosensors & Bioelectronics 2014, 58, 214-218.
30. Huang, Y.; Lin, Y.; Ran, X.; Ren, J.; Qu, X., A semipermeable enzymatic nanoreactor as an efficient modulator for reversible pH regulation. Nanoscale 2014, 6 (19), 11328-11335.
31. Huang, Y.; Lin, Y.; Ran, X.; Ren, J.; Qu, X., Self-Assembly and Compartmentalization of Nanozymes in Mesoporous Silica-Based Nanoreactors. Chemistry – A European Journal 2016, n/a-n/a.
32. Huang, Y.; Ran, X.; Lin, Y.; Ren, J.; Qu, X., Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts. Analytica Chimica Acta 2015, 870, 92-98.
33. Huang, Y.; Ran, X.; Lin, Y.; Ren, J.; Qu, X., Self-assembly of an organic-inorganic hybrid nanoflower as an efficient biomimetic catalyst for self-activated tandem reactions. Chemical Communications 2015, 51 (21), 4386-4389.
34. Huang, Z.; Pu, F.; Lin, Y.; Ren, J.; Qu, X., Modulating DNA-templated silver nanoclusters for fluorescence turn-on detection of thiol compounds. Chemical Communications 2011,47 (12), 3487-3489.
35. Ju, E.; Yang, X.; Lin, Y.; Pu, F.; Ren, J.; Qu, X., Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching. Chemical Communications 2012, 48 (95), 11662-11664.

姓名	Lin Youhui	职称职务	Associate Professor
邮箱	linyouhui@xmu.edu.cn	办公室	Room 312, Physics Building
电话		个人主页
其他信息		研究方向岗位职责	Synthesis and characterization of functionalized nanomaterials and their applications in artificial enzyme, biosensing, and logic device. Study of molecular recognition, biological functions of disease–related nucleic acids or proteins. Study of the nanomaterials-based biodevice, surface chemistry and nanomedicine.
教育和工作经历		代表性文章或专著	1. Lin Youhui; Ren, J.; Qu, X., Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes. Acc Chem Res 2014, 47 (4), 1097-1105. 2. Lin Youhui; Chen, Z.; Liu, X. Y., Using Inorganic Nanomaterials to Endow Biocatalytic Systems with Unique Features. Trends in Biotechnology 2016. 3. Lin Youhui; Zhao, A.; Tao, Y.; Ren, J.; Qu, X., Ionic Liquid as an Efficient Modulator on Artificial Enzyme System: Toward the Realization of High-Temperature Catalytic Reactions. Journal of the American Chemical Society 2013, 135 (11), 4207-4210. 4. Lin Youhui; Xu, C.; Ren, J.; Qu, X., Using Thermally Regenerable Cerium Oxide Nanoparticles in Biocomputing to Perform Label-free, Resettable, and Colorimetric Logic Operations. Angewandte Chemie-International Edition 2012, 51 (50), 12579-12583. 5. Lin Youhui; Ren, J.; Qu, X., Nano-Gold as Artificial Enzymes: Hidden Talents. Advanced Materials 2014, 26 (25), 4200-4217. 6. Lin Youhui; Wu, L.; Huang, Y.; Ren, J.; Qu, X., Positional assembly of hemin and gold nanoparticles in graphene-mesoporous silica nanohybrids for tandem catalysis. Chemical Science 2015, 6 (2), 1272-1276. 7. Lin Youhui; Tao, Y.; Pu, F.; Ren, J.; Qu, X., Combination of Graphene Oxide and Thiol-Activated DNA Metallization for Sensitive Fluorescence Turn-On Detection of Cysteine and Their Use for Logic Gate Operations. Advanced Functional Materials 2011, 21 (23), 4565-4572. 8. Lin Youhui; Huang, Y.; Ren, J.; Qu, X., Incorporating ATP into biomimetic catalysts for realizing exceptional enzymatic performance over a broad temperature range. Npg Asia Materials 2014, 6. 9. Lin Youhui; Li, Z.; Chen, Z.; Ren, J.; Qu, X., Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis. Biomaterials 2013, 34(11), 2600-2610. 10. Lin Youhui; Yin, M.; Pu, F.; Ren, J.; Qu, X., DNA-Templated Silver Nanoparticles as a Platform for Highly Sensitive and Selective Fluorescence Turn-On Detection of Dopamine. Small 2011, 7 (11), 1557-1561. 11. Lin Youhui; Chen, C.; Wang, C.; Pu, F.; Ren, J.; Qu, X., Silver nanoprobe for sensitive and selective colorimetric detection of dopamine via robust Ag-catechol interaction. Chemical Communications 2011, 47 (4), 1181-1183. 12. Lin Youhui; Tao, Y.; Ren, J.; Pu, F.; Qu, X., Highly sensitive and selective detection of thiol-containing biomolecules using DNA-templated silver deposition. Biosensors & Bioelectronics 2011, 28 (1), 339-343. 13. Yaoping Jiang; Wenhao Luo; Xiaopei Wang; Youhui Lin; Xiang Yang Liu; Enzymatic Manipulation of DNA-mediated Ensemble for Sensitive Fluorescence Detection of Glucose. RSC Adv., 2016, DOI: 10.1039/c6ra05701b. 14. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Poly(acrylic acid)-templated silver nanoclusters as a platform for dual fluorometric turn-on and colorimetric detection of mercury (II) ions. Talanta 2012, 88, 290-294. 15. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets. Analyst 2012, 137 (11), 2588-2592. 16. Tao, Y.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Incorporating Graphene Oxide and Gold Nanoclusters: A Synergistic Catalyst with Surprisingly High Peroxidase-Like Activity Over a Broad pH Range and its Application for Cancer Cell Detection. Advanced Materials 2013, 25 (18), 2594-2599. 17. Tao, Y.; Lin, Y.; Ren, J.; Qu, X., Self-assembled, functionalized graphene and DNA as a universal platform for colorimetric assays. Biomaterials 2013, 34 (20), 4810-4817. 18. Tao, Y.; Lin, Y.; Ren, J.; Qu, X., A dual fluorometric and colorimetric sensor for dopamine based on BSA-stabilized Au nanoclusters. Biosensors & Bioelectronics 2013, 42, 41-46. 19. Wang, C.; Huang, Z.; Lin, Y.; Ren, J.; Qu, X., Artificial DNA Nano-Spring Powered by Protons. Advanced Materials 2010, 22 (25), 2792-+. 20. Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohn, C.; Nakatani, K.; Qu, X., Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network. Chemistry-a European Journal 2011, 17 (29), 8189-8194. 21. Wang, C.; Tao, Y.; Lin, Y.; Ren, J.; Qu, X., A thermo-driven DNA zipper. Chemical Communications 2013, 49 (96), 11281-11283. 22. Wang, L.; Jiang, Y.; Lin, Y.; Pang, J.; Liu, X. Y., Rheological properties and formation mechanism of DC electric fields induced konjac glucomannan-tungsten gels. Carbohydrate Polymers 2016, 142, 293-299. 23. Xu, C.; Lin, Y.; Wang, J.; Wu, L.; Wei, W.; Ren, J.; Qu, X., Nanoceria-Triggered Synergetic Drug Release Based on CeO2-Capped Mesoporous Silica Host-Guest Interactions and Switchable Enzymatic Activity and Cellular Effects of CeO2. Advanced Healthcare Materials 2013, 2 (12), 1591-1599. 24. Yu, R.; Meng, Z. H.; Ye, M. D.; Lin, Y. H.; Lin, N. B.; Liu, X. Y.; Yu, W. D.; Liu, X. Y., Electrochromic performance of WO3 films: optimization by crystal network topology modification. CrystEngComm 2015, 17 (34), 6583-6590. 25. Zhou, L.; Lin, Y.; Huang, Z.; Ren, J.; Qu, X., Carbon nanodots as fluorescence probes for rapid, sensitive, and label-free detection of Hg2+ and biothiols in complex matrices. Chemical Communications 2012, 48 (8), 1147-1149. 26. Chen, Z.; Li, Z.; Lin, Y.; Yin, M.; Ren, J.; Qu, X., Bioresponsive Hyaluronic Acid-Capped Mesoporous Silica Nanoparticles for Targeted Drug Delivery. Chemistry-a European Journal 2013, 19 (5), 1778-1783. 27. Chen, Z.; Li, Z.; Lin, Y.; Yin, M.; Ren, J.; Qu, X., Biomineralization inspired surface engineering of nanocarriers for pH-responsive, targeted drug delivery. Biomaterials 2013, 34 (4), 1364-1371. 28. Chen, Z.; Lin, Y.; Zhao, C.; Ren, J.; Qu, X., Silver metallization engineered conformational switch of G-quadruplex for fluorescence turn-on detection of biothiols. Chemical Communications 2012, 48 (93), 11428-11430. 29. Chen, Z.; Zhou, L.; Zhao, A.; Zhang, Z.; Wang, Z.; Lin, Y.; Ren, J.; Qu, X., Coupling exonuclease III with DNA metallization for amplified detection of biothiols at picomolar concentration. Biosensors & Bioelectronics 2014, 58, 214-218. 30. Huang, Y.; Lin, Y.; Ran, X.; Ren, J.; Qu, X., A semipermeable enzymatic nanoreactor as an efficient modulator for reversible pH regulation. Nanoscale 2014, 6 (19), 11328-11335. 31. Huang, Y.; Lin, Y.; Ran, X.; Ren, J.; Qu, X., Self-Assembly and Compartmentalization of Nanozymes in Mesoporous Silica-Based Nanoreactors. Chemistry – A European Journal 2016, n/a-n/a. 32. Huang, Y.; Ran, X.; Lin, Y.; Ren, J.; Qu, X., Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts. Analytica Chimica Acta 2015, 870, 92-98. 33. Huang, Y.; Ran, X.; Lin, Y.; Ren, J.; Qu, X., Self-assembly of an organic-inorganic hybrid nanoflower as an efficient biomimetic catalyst for self-activated tandem reactions. Chemical Communications 2015, 51 (21), 4386-4389. 34. Huang, Z.; Pu, F.; Lin, Y.; Ren, J.; Qu, X., Modulating DNA-templated silver nanoclusters for fluorescence turn-on detection of thiol compounds. Chemical Communications 2011,47 (12), 3487-3489. 35. Ju, E.; Yang, X.; Lin, Y.; Pu, F.; Ren, J.; Qu, X., Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching. Chemical Communications 2012, 48 (95), 11662-11664.
科研基金及项目		任教课程
招生方向		荣誉奖励